BDBM50060917 ON-01910::Rigosertib

SMILES COc1ccc(cc1NCC(=O)O)CS(=O)(=O)/C=C/c2c(cc(cc2OC)OC)OC

InChI Key InChIKey=OWBFCJROIKNMGD-UHFFFAOYSA-N

Data  1 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50060917   

TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060917(ON-01910 | Rigosertib)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed