BDBM50240614 3,5-Dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-methoxy-chromen-4-one::4',7-dimethylquercetin::CHEMBL75589::Kaempferol-7,4'-dimethylether::OMBUINE::quercetin-7,4'-dimethyl ether

SMILES COc1cc(O)c2c(c1)oc(-c1ccc(OC)c(O)c1)c(O)c2=O

InChI Key InChIKey=BWORNNDZQGOKBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240614   

TargetMitogen-activated protein kinase 14(Human)
Eberhard Karls University of Tuebingen

LigandPNGBDBM50240614(Kaempferol-7,4'-dimethylether | quercetin-7,4'...)
Affinity DataIC50: 3.98E+3nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard Karls University of Tuebingen

LigandPNGBDBM50240614(Kaempferol-7,4'-dimethylether | quercetin-7,4'...)
Affinity DataIC50: 5.54E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50240614(Kaempferol-7,4'-dimethylether | quercetin-7,4'...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed