BDBM50058286 (1R,12R)::(1R,12S)::CHEMBL119561::Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4-fluorophenyl)tropane-2''beta-carboxylic acid methyl ester)(2-mercaptoethyl)amino]acetyl]-2-aminoethanethiolato]rhenium(V) oxide::O-1186::O-861::O-927::O-928::[N-[2-[(3'-N'-Propyl-3''beta-(4-fluorophenyl)tropane-2'' alpha-carboxylic acid methyl ester)(2-mercaptoethyl)amino]acetyl]-2-aminoethanethiolato]rhenium(V) oxide::[N-[2-[(3'-N'-Propyl-3''beta-(4-fluorophenyl)tropane-2''beta-carboxylic acid methyl ester)(2-mercaptoethyl)amino]acetyl]-2-aminoethanethiolato]rhenium(V) oxide

SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2CCCN1CCS[Re]2(=O)SCCN2C(=O)C1

InChI Key

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50058286   

TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter using of Cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 124nMAssay Description:Inhibition of [3H]- citalopram binding to serotonin transporter of Cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 7.38nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter using of Cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of [3H]- citalopram binding to serotonin transporter of Cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 80nMAssay Description:In vitro affinity for serotonin transporter in Rhesus (Macaca mulatta) or Cynomolgus (Macaca fasicularis) monkey striata using [3H]citalopram displac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 299nMAssay Description:In vitro affinity for serotonin transporter in Rhesus (Macaca mulatta) or Cynomolgus (Macaca fasicularis) monkey striata using [3H]citalopram displac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro affinity for serotonin transporter in Rhesus (Macaca mulatta) or Cynomolgus (Macaca fasicularis) monkey striata using [3H]citalopram displac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 3.80nMAssay Description:In vitro affinity for dopamine transporter in Rhesus (Macaca mulatta) or Cynomolgus (Macaca fasicularis) monkey striata using [3H]WIN-35428 displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 2.90nMAssay Description:In vitro affinity for dopamine transporter in Rhesus (Macaca mulatta) or Cynomolgus (Macaca fasicularis) monkey striata using [3H]WIN-35428 displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 2.90nMAssay Description:In vitro affinity for dopamine transporter in Rhesus (Macaca mulatta) or Cynomolgus (Macaca fasicularis) monkey striata using [3H]WIN-35428 displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 80nMAssay Description:In vitro affinity for serotonin transporter in Rhesus (Macaca mulatta) or Cynomolgus (Macaca fasicularis) monkey striata using [3H]citalopram displac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50058286(Diastereiosomer of [N-[2-[(3'-N'-Propyl-3''beta-(4...)
Affinity DataIC50: 2.90nMAssay Description:In vitro affinity for dopamine transporter in Rhesus (Macaca mulatta) or Cynomolgus (Macaca fasicularis) monkey striata using [3H]WIN-35428 displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed