BDBM50556205 BAY 1841788::BAY-1841788::BAY1841788::Darolutamide::Nubeqa::Odm-201

SMILES C[C@@H](Cn1ccc(n1)-c1ccc(C#N)c(Cl)c1)NC(=O)c1cc([nH]n1)C(C)O

InChI Key InChIKey=BLIJXOOIHRSQRB-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50556205   

TargetAndrogen receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50556205(Darolutamide | Odm-201 | BAY 1841788 | BAY-1841788...)
Affinity DataIC50: 26nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50556205(Darolutamide | Odm-201 | BAY 1841788 | BAY-1841788...)
Affinity DataIC50: 48nMAssay Description:Antagonist activity at CMV-tagged full length wild type human AR expressed in HEK293 cells co-transfected with GRE-LUC and CMV-renilla LUC assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50556205(Darolutamide | Odm-201 | BAY 1841788 | BAY-1841788...)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]-PDBu from human recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50556205(Darolutamide | Odm-201 | BAY 1841788 | BAY-1841788...)
Affinity DataKi:  11nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50556205(Darolutamide | Odm-201 | BAY 1841788 | BAY-1841788...)
Affinity DataKi:  4.23E+3nMAssay Description:Displacement of [3H]mibolerone from GST-tagged wild type AR ligand binding domain (unknown origin) incubated for 16 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed