BDBM50225362 Norprolac::QUINAGOLIDE

SMILES [H][C@]12C[C@@H](CN(CCC)[C@]1([H])Cc1cccc(O)c1C2)NS(=O)(=O)N(CC)CC

InChI Key InChIKey=GDFGTRDCCWFXTG-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50225362   

LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]WB 4101 whole rat brain alpha 1-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 7.40E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]clonidine (Clon) rat brain minus cerebellum Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]WB 4101 whole rat brain alpha 1-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity was evaluated against [3H]dopamine (DA) calf caudate dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone rat frontal cortex (SPFC) serotonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]clonidine (Clon) rat brain minus cerebellum Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone calf caudate (SPC) dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone calf caudate (SPC) dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone rat frontal cortex (SPFC) serotonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 75nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]dopamine (DA),calf caudate dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]spiperone rat frontal cortex (SPFC) serotonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity was evaluated against [3H]spiperone calf caudate (SPC) dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 5.10E+3nMAssay Description:In vitro inhibitory activity against serotonin receptor from rat frontal cortex using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]serotonin (5-HT) whole rat brain serotonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]WB 4101 whole rat brain alpha 1-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]serotonin (5-HT) whole rat brain serotonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]serotonin (5-HT) whole rat brain serotonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 75nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]dopamine (DA),calf caudate dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 7.40E+3nMAssay Description:In vitro inhibitory activity was evaluated against,[3H]clonidine (Clon) rat brain minus cerebellum Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2018
Entry Details Article
PubMed
TargetMetalloproteinase inhibitor 3(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibitory activity against serotonin receptor from whole rat brain using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 7.80E+3nMAssay Description:In vitro inhibitory activity against alpha-1 adrenergic receptor from whole rat brain using [3H]WB-4101 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 5.60E+3nMAssay Description:In vitro inhibitory activity against alpha-2 adrenergic receptor from rat brain minus cerebellum using [3H]clonidine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 48nMAssay Description:In vitro inhibitory activity against dopamine receptor from calf caudate using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetD(1A)/D(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50225362(Norprolac | QUINAGOLIDE)
Affinity DataIC50: 190nMAssay Description:In vitro inhibitory activity against dopamine receptor from calf caudate using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed