BDBM82552 CAS_111555-58-9::NTB::naltrindolebenzofuran

SMILES c1ccc2c(c1)c3c(o2)[C@H]4[C@@]56CCN([C@@H]([C@@]5(C3)O)Cc7c6c(c(cc7)O)O4)CC8CC8

InChI Key InChIKey=ZHVWWEYETMPAMX-UHFFFAOYSA-N

Data  13 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 82552   

TargetDelta-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  0.0130nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor delta using [3H]DADLE as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  4.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  6.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  10.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  12.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  18.8nMAssay Description:Compound was evaluated for the binding affinity to Opioid receptor mu using [3H]DAMGO as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM82552(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
Affinity DataKi:  154nMAssay Description:Compound was evaluated for the binding affinity to opioid receptor kappa using [3H]-EK as radioligand in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed