BDBM50056933 (E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-9-ylmethyl) ester::CHEMBL366861::NSC-685588::fumarprotocetraric acid

SMILES Cc1cc(O)c(C=O)c2Oc3c(C)c(C(O)=O)c(O)c(COC(=O)\C=C\C(O)=O)c3OC(=O)c12

InChI Key InChIKey=VEGGRTFDFMUBPD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50056933   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1&2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1&2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 8-((4-chlorophenyl)amino)naphthalene-1-sulfonic acid binding to CDK2 (unknown origin) measured after 2 hrs by fluorescence based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50056933((E)-But-2-enedioic acid mono-(7-carboxy-4-formyl-3...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of 8-((4-chlorophenyl)amino)naphthalene-1-sulfonic acid binding to CDK2 (unknown origin) incubated for 2 hrs in presence of staurosporine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed