BDBM50056915 2-Chloro-3-hydroxy-8-methoxy-1,6,9-trimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-4-carbaldehyde::CHEMBL285415::NSC-646008

SMILES COc1cc(C)c2Oc3c(C=O)c(O)c(Cl)c(C)c3C(=O)Oc2c1C

InChI Key InChIKey=LVGKNESDSKGROR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50056915   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056915(NSC-646008 | 2-Chloro-3-hydroxy-8-methoxy-1,6,9-tr...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056915(NSC-646008 | 2-Chloro-3-hydroxy-8-methoxy-1,6,9-tr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056915(NSC-646008 | 2-Chloro-3-hydroxy-8-methoxy-1,6,9-tr...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056915(NSC-646008 | 2-Chloro-3-hydroxy-8-methoxy-1,6,9-tr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056915(NSC-646008 | 2-Chloro-3-hydroxy-8-methoxy-1,6,9-tr...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056915(NSC-646008 | 2-Chloro-3-hydroxy-8-methoxy-1,6,9-tr...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibitory concentration of compound against disintegration (reversal of strand transfer)of HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed