BDBM50008347 5-(2-(diethylamino)ethylamino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one::5-(2-Diethylamino-ethylamino)-8-hydroxy-2,10b-diaza-aceanthrylen-6-one(2.0MHCl.1.0MH2O)::CHEMBL338604::NSC-645809

SMILES CCN(CC)CCNc1ccc2ncn3c2c1c(=O)c1cc(O)ccc31

InChI Key InChIKey=CUNDRHORZHFPLY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008347   

TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50008347(NSC-645809 | 5-(2-(diethylamino)ethylamino)-8-hydr...)
Affinity DataIC50: 126nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50008347(NSC-645809 | 5-(2-(diethylamino)ethylamino)-8-hydr...)
Affinity DataIC50: 148nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A9(Human)
Gdansk University of Technology

Curated by ChEMBL
LigandPNGBDBM50008347(NSC-645809 | 5-(2-(diethylamino)ethylamino)-8-hydr...)
Affinity DataKi:  9.58E+5nMAssay Description:Inhibition of human recombinant UGT1A9 activity expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed