BDBM50298486 5-(4-chlorophenylamino)-2-methyl-9-nitro-5H-chromeno[4,3-b]pyridine-3-carbonitrile::CHEMBL572637::NSC-613604

SMILES Cc1nc-2c(cc1C#N)C(Nc1ccc(Cl)cc1)Oc1ccc(cc-21)[N+]([O-])=O

InChI Key InChIKey=DAHDDFCIAFXETP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298486   

TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50298486(NSC-613604 | 5-(4-chlorophenylamino)-2-methyl-9-ni...)
Affinity DataIC50: 678nMAssay Description:Inhibition of human placental aromatase assessed as conversion of [1-beta-3H]androstenedione to [1beta-3H]estrone after 20 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50298486(NSC-613604 | 5-(4-chlorophenylamino)-2-methyl-9-ni...)
Affinity DataKi:  385nMAssay Description:Competitive inhibition of human placental aromatase by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed