BDBM50056879 4-(2,4-Dihydroxy-phenyl)-N-hydroxy-2-[(Z)-hydroxyimino]-4-oxo-butyramide::CHEMBL174172::NSC-371056

SMILES ONC(=O)C(NO)=CC(=O)c1ccc(O)cc1O

InChI Key InChIKey=ZXCZCRNTFXPCFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056879   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056879(4-(2,4-Dihydroxy-phenyl)-N-hydroxy-2-[(Z)-hydroxyi...)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibitory concentration against purified recombinant integrase by strand transfer in vitro assay (experiment 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056879(4-(2,4-Dihydroxy-phenyl)-N-hydroxy-2-[(Z)-hydroxyi...)
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibitory concentration against purified recombinant integrase by 3'-processing in vitro assay (experiment 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056879(4-(2,4-Dihydroxy-phenyl)-N-hydroxy-2-[(Z)-hydroxyi...)
Affinity DataIC50: 3.58E+4nMAssay Description:Inhibitory concentration against purified recombinant integrase by strand transfer in vitro assay (experiment 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056879(4-(2,4-Dihydroxy-phenyl)-N-hydroxy-2-[(Z)-hydroxyi...)
Affinity DataIC50: 7.13E+4nMAssay Description:Inhibitory concentration against purified recombinant integrase by 3'-processing in vitro assay (experiment 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed