BDBM50179183 CHEMBL576840::NSC-3198

SMILES OC(=O)C(CSSCC(NC(=O)Cc1ccccc1)C(O)=O)NC(=O)Cc1ccccc1

InChI Key InChIKey=DWRCRIMPBCLETK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50179183   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179183(CHEMBL576840 | NSC-3198)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of human recombinant TDP1 using 5'-[32P]-labeled N14Y as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Zebrafish)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179183(CHEMBL576840 | NSC-3198)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of zebra fish recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Mouse)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179183(CHEMBL576840 | NSC-3198)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179183(CHEMBL576840 | NSC-3198)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50179183(CHEMBL576840 | NSC-3198)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of amyloid beta (1 to 40) (unknown origin) aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed