BDBM50088352 4-Dimethylamino-3,6,12-trihydroxy-6,10-dimethyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid [4-(guanidino-imino-methyl)-piperazin-1-ylmethyl]-amide::CHEMBL292992::NSC-118695

SMILES CN(C)[C@H]1[C@@H]2C[C@H]3C(C(=O)C2C(=O)C(C(=O)NCN2CCN(CC2)C(N)=NC(N)=N)C1=O)C(=O)c1c(C)cccc1C3(C)O

InChI Key InChIKey=NOIJIWMKMAOMDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088352   

TargetIntegrase(Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50088352(NSC-118695 | 4-Dimethylamino-3,6,12-trihydroxy-6,1...)
Affinity DataIC50: 300nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50088352(NSC-118695 | 4-Dimethylamino-3,6,12-trihydroxy-6,1...)
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed