BDBM50000215 NS-49

SMILES CS(=O)(=O)Nc1ccc(F)c(c1)[C@@H](O)CN

InChI Key InChIKey=XYLJNMCMDOOJRW-UHFFFAOYSA-N

Data  2 KI  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50000215   

TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataEC50: <1.00E+5nMAssay Description:Activation of recombinant human adrenergic, alpha-1D receptor expressed in rat-1 fibroblasts assayed via calcium mobilization through Gq coupled PLC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataEC50: <1.00E+5nMAssay Description:Activation of recombinant human adrenergic, alpha-1B receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataEC50:  316nMAssay Description:Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataEC50:  158nMAssay Description:Agonist potency at Alpha-1 adrenergic receptor assayed in rat-1 fibroblasts expressing human Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist potency at Alpha-1B adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist potency at Alpha-1D adrenergic receptor assayed in rat-1 fibroblasts expressing human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist potency at Alpha-2C adrenergic receptor assayed in CHO cells expressing human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist potency at Alpha-2A stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataKi:  1.12E+3nMAssay Description:Affinity to Alpha-1 adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000215(NS-49)
Affinity DataKi:  1.12E+4nMAssay Description:Affinity to human Alpha-1B adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed