BDBM50154449 5-[4-(2-Amino-ethylamino)-3-nitro-phenyl]-6-ethyl-pyrimidine-2,4-diamine::CHEMBL84440::NCI-372939::cid_3449946

SMILES CCc1nc(N)nc(N)c1-c1ccc(NCCN)c(c1)[N+]([O-])=O

InChI Key InChIKey=XYSUDZRZSXTBRQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50154449   

TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50154449(CHEMBL84440 | cid_3449946 | 5-[4-(2-Amino-ethylami...)
Affinity DataIC50: 5.66E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50154449(CHEMBL84440 | cid_3449946 | 5-[4-(2-Amino-ethylami...)
Affinity DataIC50: 6.08E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50154449(CHEMBL84440 | cid_3449946 | 5-[4-(2-Amino-ethylami...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetCytochrome P450 2D6(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50154449(CHEMBL84440 | cid_3449946 | 5-[4-(2-Amino-ethylami...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed