BDBM50445351 NAMOLINE

SMILES [O-][N+](=O)c1ccc2oc(c(Cl)c(=O)c2c1)C(F)(F)F

InChI Key InChIKey=DYEGRZKBJMKSKD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50445351   

TargetLysine-specific histone demethylase 1A(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50445351(NAMOLINE)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of GST-tagged LSD1 (2 to 852 residues) (unknown origin) using H3K4me2 substrate assessed as reduction in H2O2 production by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50445351(NAMOLINE)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of GST-tagged recombinant LSD1 (2 to 852) (unknown origin) using H3K4me2 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50445351(NAMOLINE)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50445351(NAMOLINE)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of GST-tagged human LSD1 (2 to 852 residues) expressed in baculovirus using H3K4me2 as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed