BDBM669879 Monomer ::US20240132489, Compound 112

SMILES FC(F)(F)c1cnc(N[C@@H]2CCCNC2)nc1-c1c[nH]c2nc(ccc12)C1CCCCO1

InChI Key InChIKey=NFSYJPOVLYTWLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669879   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Gt Apeiron Therapeutics

US Patent
LigandPNGBDBM669879(US20240132489, Compound 112 | Monomer )
Affinity DataIC50: 5.82nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent