BDBM50202290 2,3-dimethoxy-7,7-dimethyl-7H-dibenzo[de,g]quinoline-1,9-diol::CHEMBL257958::Melosmine

SMILES COc1c(O)c2-c3ccc(O)cc3C(C)(C)c3nccc(c1OC)c23

InChI Key InChIKey=CUEIWVZJOPCMPT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50202290   

LigandPNGBDBM50202290(2,3-dimethoxy-7,7-dimethyl-7H-dibenzo[de,g]quinoli...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50202290(2,3-dimethoxy-7,7-dimethyl-7H-dibenzo[de,g]quinoli...)
Affinity DataIC50: 2.46E+4nMAssay Description:Displacement of [3H]DA from rat DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50202290(2,3-dimethoxy-7,7-dimethyl-7H-dibenzo[de,g]quinoli...)
Affinity DataIC50: 8.00E+4nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50202290(2,3-dimethoxy-7,7-dimethyl-7H-dibenzo[de,g]quinoli...)
Affinity DataIC50: 1.25E+4nMAssay Description:Displacement of [3H]SCH-23390 from rat dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50202290(2,3-dimethoxy-7,7-dimethyl-7H-dibenzo[de,g]quinoli...)
Affinity DataIC50: 5.92E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed