BDBM50575174 Mavacamten

SMILES C[C@@H](c1ccccc1)NC2=CC(=O)N(C(=O)N2)C(C)C

InChI Key InChIKey=RLCLASQCAPXVLM-UHFFFAOYSA-N

Data  2 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575174   

TargetCytochrome P450 3A4(Human)
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575174(Mavacamten)
Affinity DataEC50:  2.20E+3nMAssay Description:Induction of CYP3A4 in human hepatocytes assessed as mRNA expression incubated for 3 days by RT-RTPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575174(Mavacamten)
Affinity DataEC50:  5.10E+3nMAssay Description:Induction of CYP2B6 in human hepatocytes assessed as mRNA expression incubated for 3 days by RT-RTPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed