BDBM50295923 4'-Methoxy-3'-(E)-propenyl)-5-(2-propenyl)-biphenyl-2-ol::CHEMBL549698::Magreth-3a::Magreth-3b

SMILES COc1ccc(cc1\C=C\C)-c1cc(CC=C)ccc1O

InChI Key InChIKey=IDZDKMNEPBYXQX-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50295923   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295923(Magreth-3a | Magreth-3b | CHEMBL549698 | 4'-Methox...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295923(Magreth-3a | Magreth-3b | CHEMBL549698 | 4'-Methox...)
Affinity DataIC50: 200nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295923(Magreth-3a | Magreth-3b | CHEMBL549698 | 4'-Methox...)
Affinity DataIC50: 700nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

LigandPNGBDBM50295923(Magreth-3a | Magreth-3b | CHEMBL549698 | 4'-Methox...)
Affinity DataKi:  40.8nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

LigandPNGBDBM50295923(Magreth-3a | Magreth-3b | CHEMBL549698 | 4'-Methox...)
Affinity DataKi:  59.1nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

LigandPNGBDBM50295923(Magreth-3a | Magreth-3b | CHEMBL549698 | 4'-Methox...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

LigandPNGBDBM50295923(Magreth-3a | Magreth-3b | CHEMBL549698 | 4'-Methox...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed