BDBM50295926 4'-O-methylhonokiol, MH::4-methoxyhonokiol::5,3'-Diallyl-4'-methoxy-biphenyl-2-ol::CHEMBL89700::Magreth-14a::Methylhonokiol

SMILES COc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O

InChI Key InChIKey=OQFHJKZVOALSPV-UHFFFAOYSA-N

Data  5 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50295926   

TargetProstaglandin G/H synthase 1(Sheep)
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataIC50: 100nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2(Human)
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataEC50:  2.72E+4nMAssay Description:Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataKi:  43.9nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataKi:  138nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataKi:  790nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed