BDBM85380 3-O-Methyldopamine hydrochloride::CAS_1477-68-5::MT-3::cid_11957621

SMILES COc1cc(CCN)ccc1O

InChI Key InChIKey=DIVQKHQLANKJQO-UHFFFAOYSA-N

Data  3 KI  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 85380   

TargetGuanine nucleotide-binding protein subunit alpha-15(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetTrace amine-associated receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataIC50: 2.16E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetTrace amine-associated receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataEC50:  2.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataIC50: 2.99E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetTrace amine-associated receptor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataEC50:  308nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Bovine)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Pig)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM85380(CAS_1477-68-5 | cid_11957621 | 3-O-Methyldopamine ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed