BDBM50610836 MSC-4381
SMILES CCOc1ccc(c2ncccc12)S(=O)(=O)Nc1ccc(Cl)cc1C#Cc1cnc(cc1OC)C(O)=O
InChI Key InChIKey=FNBUZGRPJLEIMO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50610836
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+7nMAssay Description:Inhibition of human MCT4 in human MIA PaCa-2 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 6.38E+5nMAssay Description:Inhibition of human MCT4 in human RT-4 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured a...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair