BDBM50085327 CHEMBL108166::MRS 2286::Phosphoric acid mono-[4-(2-chloro-6-methylamino-purin-9-yl)-2-phosphonooxymethyl-butyl] ester

SMILES CNc1nc(Cl)nc2n(CCC(COP(O)(O)=O)COP(O)(O)=O)cnc12

InChI Key InChIKey=PNKXGOOONVKRHI-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085327   

TargetP2Y purinoceptor 1(Wild turkey)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085327(MRS 2286 | Phosphoric acid mono-[4-(2-chloro-6-met...)
Affinity DataIC50: 840nMAssay Description:Inhibitory concentration against P2Y1 receptor in turkey erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085327(MRS 2286 | Phosphoric acid mono-[4-(2-chloro-6-met...)
Affinity DataEC50:  840nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085327(MRS 2286 | Phosphoric acid mono-[4-(2-chloro-6-met...)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at P2Y1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085327(MRS 2286 | Phosphoric acid mono-[4-(2-chloro-6-met...)
Affinity DataIC50: 840nMAssay Description:Agonist activity at human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed