BDBM50070097 (Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6,7-dihydroindolizin-8(5H)-one::6-(4-Chloro-phenyl)-7-[1-pyridin-4-yl-meth-(Z)-ylidene]-6,7-dihydro-5H-indolizin-8-one::CHEMBL9165::MR-20492

SMILES Clc1ccc(cc1)C1Cn2cccc2C(=O)\C1=C/c1ccncc1

InChI Key InChIKey=OMGJLQMHGRFTAP-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070097   

TargetAromatase(Human)
Centre D'Etudes Et De Recherche Sur Le MéDicament De Normandie

Curated by ChEMBL
LigandPNGBDBM50070097(MR-20492 | (Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylm...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human aromatase cytochrome P450 19A1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Centre D'Etudes Et De Recherche Sur Le MéDicament De Normandie

Curated by ChEMBL
LigandPNGBDBM50070097(MR-20492 | (Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylm...)
Affinity DataIC50: 150nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Centre D'Etudes Et De Recherche Sur Le MéDicament De Normandie

Curated by ChEMBL
LigandPNGBDBM50070097(MR-20492 | (Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylm...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Centre D'Etudes Et De Recherche Sur Le MéDicament De Normandie

Curated by ChEMBL
LigandPNGBDBM50070097(MR-20492 | (Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylm...)
Affinity DataKi:  10nMAssay Description:Inhibition constant for human aromatase cytochrome P450 19A1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed