BDBM442746 MPI1

SMILES O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=JKMYXNKXJWIHOA-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 442746   

TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM442746(MPI1)
Affinity DataIC50: 100nMAssay Description:Inhibition of SARS-CoV-2 main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM442746(MPI1)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM442746(MPI1)
Affinity DataKi:  98nM IC50: 100nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed