BDBM50368906 CHEMBL25448::MK-386

SMILES CC(C)CCCC(C)[C@H]1CCC2C3[C@@H](C)CC4N(C)C(=O)CC[C@]4(C)C3CC[C@]12C

InChI Key InChIKey=XUTZDXHKQDPUMA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50368906   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50368906(MK-386 | CHEMBL25448)
Affinity DataIC50: 154nMAssay Description:Inhibition of human 5-alpha reductase 2 isozyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50368906(MK-386 | CHEMBL25448)
Affinity DataIC50: 0.900nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50368906(MK-386 | CHEMBL25448)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50368906(MK-386 | CHEMBL25448)
Affinity DataIC50: 154nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50368906(MK-386 | CHEMBL25448)
Affinity DataIC50: 154nMAssay Description:Inhibition of type 2 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50368906(MK-386 | CHEMBL25448)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed