BDBM50135883 (2R)-1-(2,6-dimethylphenoxy)propan-2-amine::(R)-1-(2,6-dimethylphenoxy)propan-2-amine::(R)-2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine::CHEMBL147507::MEXILETINE

SMILES C[C@@H](N)COc1c(C)cccc1C

InChI Key InChIKey=VLPIATFUUWWMKC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135883   

TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50135883((R)-1-(2,6-dimethylphenoxy)propan-2-amine | (2R)-1...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50135883((R)-1-(2,6-dimethylphenoxy)propan-2-amine | (2R)-1...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50135883((R)-1-(2,6-dimethylphenoxy)propan-2-amine | (2R)-1...)
Affinity DataEC50:  2.29E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed