BDBM50225502 MDL-19205::Piroximone

SMILES CCc1[nH]c(=O)[nH]c1C(=O)c1ccncc1

InChI Key InChIKey=OQGWJZOWLHWFME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50225502   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50225502(MDL-19205 | Piroximone)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of cAMP PDE III enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50225502(MDL-19205 | Piroximone)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of low Km cyclic AMP phosphodiesterase PDE III of canine ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50225502(MDL-19205 | Piroximone)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details Article
PubMed