BDBM86238 CAS_3050061::MDA,S(+)::NSC_3050061

SMILES C[C@H](N)Cc1ccc2OCOc2c1

InChI Key InChIKey=NGBBVGZWCFBOGO-UHFFFAOYSA-N

Data  4 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 86238   

TargetTrace amine-associated receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataEC50:  6.57E+3nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataEC50:  1.35E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataEC50:  98nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataEC50:  100nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataEC50: >1.00E+4nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataEC50:  3.85E+3nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetNorepinephrine transporter(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataKi:  98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2012
Entry Details Article
PubMed