BDBM50210556 CHEMBL390912::MCL-458::oxazole-2-one-N-cyclobutylmethylmorphinan

SMILES O=c1[nH]c2cc3C[C@@H]4[C@@H]5CCCC[C@]5(CCN4CC4CCC4)c3cc2o1

InChI Key InChIKey=PSLNEDDFOIXXGT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210556   

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50210556(MCL-458 | oxazole-2-one-N-cyclobutylmethylmorphina...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50210556(MCL-458 | oxazole-2-one-N-cyclobutylmethylmorphina...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50210556(MCL-458 | oxazole-2-one-N-cyclobutylmethylmorphina...)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed