BDBM225898 MAP16::US9592235, Example 248::US9855269, Compound 95

SMILES Nc1ncnc2ccc(nc12)N1CCC(Cc2ccccn2)C1

InChI Key InChIKey=WZKNLUWTEBWEOX-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 225898   

LigandPNGBDBM225898(MAP16 | US9592235, Example 248 | US9855269, Compou...)
Affinity DataIC50: 65.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM225898(MAP16 | US9592235, Example 248 | US9855269, Compou...)
Affinity DataIC50: 65.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM225898(MAP16 | US9592235, Example 248 | US9855269, Compou...)
Affinity DataKi:  78.3nM IC50: 65.7nMAssay Description:Z'Lyte AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R