BDBM50047021 2-(6-(2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone::2-[6-(2-Hydroxy-2-phenyl-ethyl)-1-methyl-piperidin-2-yl]-1-phenyl-ethanone::2-[6-(2-Hydroxy-2-phenyl-ethyl)-1-methyl-piperidin-2-yl]-1-phenyl-ethanone (lobeline)::CHEMBL15476::Lobeline::Lobeline, (-)::Lobeline,Alpha

SMILES C[N@@]1[C@H](CCC[C@H]1CC(=O)c2ccccc2)C[C@H](c3ccccc3)O

InChI Key InChIKey=MXYUKLILVYORSK-UHFFFAOYSA-N

Data  17 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50047021   

TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
The Danish University of Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  1.92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Danish University of Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  6.39nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
In Depth
Date in BDB:
11/25/2011
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Danish University of Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  12.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
R. J. Reynolds Tobacco

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  15.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Danish University of Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
The Danish University of Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  280nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
The Danish University of Pharmaceutical Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  480nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  1.87E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  5.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi:  8.88E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM50047021(Lobeline | 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed