BDBM50048093 CHEBI:610092::CHEMBL503075::Lactoside::Methyl Beta-D-Lactoside

SMILES CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O

InChI Key InChIKey=FHNIYFZSHCGBPP-UHFFFAOYSA-N

Data  1 IC50  7 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50048093   

TargetTrans-sialidase [3-643](Trypanosoma cruzi)
Universidade Federal Do Rio De Janeiro

LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  1.50E+4nMT: 2°CAssay Description:Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetTrans-sialidase [3-643,Y342H](Trypanosoma cruzi)
Universidade Federal Do Rio De Janeiro

LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  5.20E+4nMT: 2°CAssay Description:Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  1.90E+5nMAssay Description:Antagonist activity against human galectin 1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-3(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  2.20E+5nMAssay Description:Antagonist activity against human galectin 3 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-7(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  1.10E+5nMAssay Description:Antagonist activity against human galectin 7 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-8(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  6.20E+4nMAssay Description:Antagonist activity against human galectin 8 N-terminal domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataKd:  2.30E+4nMAssay Description:Antagonist activity against human galectin 9 N-terminal domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50048093(CHEBI:610092 | Methyl Beta-D-Lactoside | Lactoside...)
Affinity DataIC50: 7.40E+6nMAssay Description:Inhibition of asialofetuin binding to human recombinant Gal-1 transfected in Escherichia coli BL21 (DE3) incubated for 2 hrs by competitive solid-pha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed