BDBM50607920 LY 3023414::LY-3023414::LY3023414::Ly-3023414::SAMOTOLISIB::Samotolisib
SMILES CO[C@@H](C)Cn1c2c(cnc3ccc(cc23)-c2cncc(c2)C(C)(C)O)n(C)c1=O
InChI Key InChIKey=ACCFLVVUVBJNGT-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50607920
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant human P13Kalpha in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 165nMAssay Description:Inhibition of mTOR (unknown origin) by lanthascreen kinase assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of P13Kgamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of P13Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of P13Kbeta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant PI3Kalpha in presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of human recombinant PI3Kbeta in presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 165nMAssay Description:Inhibition of mTOR (unknown origin) by Lanthascreen kinase assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Calabria
Curated by ChEMBL
University of Calabria
Curated by ChEMBL