BDBM50281731 (4S,5R)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothioic acid (4-chloro-3-trifluoromethyl-phenyl)-amide::CHEMBL169274::LY-294920

SMILES FC(F)(F)c1cc(NC(=S)N2NC(=O)[C@H]([C@@H]2c2ccccc2)c2ccccc2)ccc1Cl

InChI Key InChIKey=DFOIEDQSOJASSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281731   

LigandPNGBDBM50281731((4S,5R)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Affinity DataIC50: 550nMpH: 7.4Assay Description:The compound was tested for its activity to inhibit the binding of [125I]CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281731((4S,5R)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Affinity DataIC50: 810nMAssay Description:The compound was tested for its activity to inhibit the binding of [3H]-L-364,718 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article