BDBM50036749 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)heptyloxy]phenyl}-1-ethanone; with sodium ion::CHEMBL45460::LY-255283::Sodium salt of 1-{5-Ethyl-2-hydroxy-4-[6-methyl-6-(2H-tetrazol-5-yl)-heptyloxy]-phenyl}-ethanone::sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)heptyloxy]phenyl}-1-ethanone

SMILES CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1

InChI Key InChIKey=FKBUCAKNDBEHSA-UHFFFAOYSA-M

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50036749   

TargetLeukotriene B4 receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,...)
Affinity DataIC50: 2.87E+3nMAssay Description:LTB4-induced up-regulation of CD11b/CD18 in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,...)
Affinity DataIC50: 85nMAssay Description:Compound was evaluated for receptor binding against [3H]LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetLeukotriene B4 receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,...)
Affinity DataIC50: 85nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,...)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of LTB4-induced human neutrophil CD11b/CD18 integrin up-regulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,...)
Affinity DataKi:  66nMAssay Description:Binding affinity against Guinea pig membrane LTB4 Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,...)
Affinity DataKi:  78nMAssay Description:Compound was evaluated for receptor binding against [3H]LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetLeukotriene B4 receptor 1/2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,...)
Affinity DataKi:  78nMAssay Description:In vitro inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(sodium 1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,...)
Affinity DataKi:  128nMAssay Description:Binding affinity against human neutrophil Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article