BDBM50242639 5-((4-Azido-3-iodobenzamido)methyl)-N,N-dimethyl-1H-tetrazole-1-carboxamide::CHEMBL486037::LY-2318912

SMILES CN(C)C(=O)n1nnnc1CNC(=O)c1ccc(N=[N+]=[N-])c(I)c1

InChI Key InChIKey=QJNXEOBTVAWQME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242639   

TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242639(5-((4-Azido-3-iodobenzamido)methyl)-N,N-dimethyl-1...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242639(5-((4-Azido-3-iodobenzamido)methyl)-N,N-dimethyl-1...)
Affinity DataIC50: 23nMAssay Description:Inhibition of FAAH mediated [14C]anandamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed