BDBM50032762 (4aR,10bR)-8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::(R)-8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::4,8-Dimethyl-4a,5,6,10b-tetrahydro-4H-benzo[f]quinolin-3-one::8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::Bexlosteride::CHEMBL24955::LY-191704

SMILES CN1C2CCc3cc(Cl)ccc3[C@H]2CCC1=O

InChI Key InChIKey=WQBIOEFDDDEARX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50032762   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50032762(LY-191704 | Bexlosteride | 8-Chloro-4-methyl-1,4,4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibition against human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50032762(LY-191704 | Bexlosteride | 8-Chloro-4-methyl-1,4,4...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50032762(LY-191704 | Bexlosteride | 8-Chloro-4-methyl-1,4,4...)
Affinity DataIC50: 7.90nMAssay Description:In vitro inhibitory concentration required to inhibit Steroid 5-alpha-reductase type 1 in cultured Hs 68 human foreskin fibroblast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article