BDBM50311316 CHEMBL1077739::LDN-211904::N-(2-chlorophenyl)-6-(piperidin-4-yl)imidazo[1,2-a]pyridine-3-carboxamide, oxalate salt

SMILES c1ccc(c(c1)NC(=O)c2cnc3n2cc(cc3)C4CCNCC4)Cl

InChI Key InChIKey=DGSMEFWSLXFLQA-UHFFFAOYSA-N

Data  2 IC50  1 Kd  5 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50311316   

TargetEphrin type-A receptor 2 [596-900](Human)
Technical University of Munich

LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataKd:  165nMAssay Description:Kinobeads competition assays were performed in 96-well format as previously described using mixed protein lysates of four cancer cell lines (K-562, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-A receptor 2 [596-900](Human)
Technical University of Munich

LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataIC50: 4.10nMAssay Description:Refer to Reaction Biology Corps.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataEC50:  270nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-A receptor 4(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataEC50:  48nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataEC50:  4.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataEC50: >5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataEC50: >5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed