BDBM50569863 Abediterol::LAS-100977::LAS100977

SMILES O[C@@H](CNCCCCCCOCC(F)(F)c1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=SFYAXIFVXBKRPK-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50569863   

TargetBeta-2 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50569863(Abediterol | LAS-100977 | LAS100977)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of 3H]CGP12177 binding to human beta2 adrenoceptor expressed in sf9 cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50569863(Abediterol | LAS-100977 | LAS100977)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at beta2 adrenoceptor human bronchi assessed as induction of maximum relaxationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50569863(Abediterol | LAS-100977 | LAS100977)
Affinity DataEC50:  36nMAssay Description:Inhibition of 3H]CGP12177 binding to human beta1 adrenoceptor expressed in sf9 cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed