BDBM50072297 (S)-5-Acetimidoylamino-2-amino-pent::(S)-5-Acetimidoylamino-2-amino-pentanoic acid::5-Acetimidoylamino-2-(S)-amino-pentanoic acid::CHEMBL11471::L-NIO, 12::N5-(1-iminoethyl)-L-ornithine::N5-IMINOETHYL-L-ORNITHINE

SMILES CC(N)=NCCC[C@H](N)C(O)=O

InChI Key InChIKey=UYZFAUAYFLEHRC-UHFFFAOYSA-N

Data  11 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50072297   

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Mouse)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 3.90E+3nMAssay Description:Tested for inhibition of mouse inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 9.00E+3nMAssay Description:Compound was evaluated for inhibitory activity against iNOS obtained from RAW 264.7 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration against human endothelial nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration against human inducible nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory concentration against human neuronal nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 800nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Rat)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 2.20E+3nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  230nMAssay Description:Inhibitory constant for the inhibition of human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNitric oxide synthase, inducible(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  340nMAssay Description:Inhibitory constant for the inhibition of human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNitric oxide synthase, endothelial(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  810nMAssay Description:Inhibitory constant for the inhibition of human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNitric oxide synthase, inducible(Mouse)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  1.42E+3nMAssay Description:The compound was tested for competitive antagonist of Nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human nNOS assessed as inhibition constant measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, brain(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibition of mouse iNOS overexpressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, brain(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  9.90E+5nMAssay Description:Inhibition of human DDAH1 expressed using SMTC as substrate assessed as inhibition constant measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataKi:  9.90E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed