BDBM50254450 (S)-2-Amino-5-propionimidoylamino-pentanoic acid::CHEMBL507472::L-IPO, 13::N5-(1-iminopropyl)-L-ornithine

SMILES [H]/N=C(/CC)NCCC[C@@H](C(=O)O)N

InChI Key InChIKey=ZYIBCZWVLDODOL-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50254450   

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
The University of Texas

LigandPNGBDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human DDAH1 expressed in Escherichia coli BL21 cells assessed as inhibition constant measured after 30 mins by calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50254450(L-IPO, 13 | (S)-2-Amino-5-propionimidoylamino-pent...)
Affinity DataKi:  1.45E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed