BDBM153698 L-CS319

SMILES C1[C@H](N2[C@@H](S1)CS[C@@H]2CS)C(=O)O

InChI Key InChIKey=ZTWVMVSSSBGFHH-UHFFFAOYSA-N

Data  3 KI

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 153698   

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153698(L-CS319)
Affinity DataKi:  3.70E+3nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVIM-24(Pseudomonas aeruginosa (g-Proteobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153698(L-CS319)
Affinity DataKi:  6.00E+3nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Xihua University

Curated by ChEMBL
LigandPNGBDBM153698(L-CS319)
Affinity DataKi:  7.00E+3nMAssay Description:Binding affinity to NDM1 (unknown origin) assessed as inhibition constant by measuring imipenem hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)