BDBM50021581 CHEMBL414850::L-870810

SMILES O\C(=N/Cc1ccc(F)cc1)c1nc(N2CCCCS2(=O)=O)c2cccnc2c1O

InChI Key InChIKey=DIDKWCOCQJWMDJ-UHFFFAOYSA-N

Data  15 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50021581   

TargetIntegrase(Human immunodeficiency virus type 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV1 integrase bound with donor DNA-SPA beads using 3'-end fluorescein isothiocyanate labeled target DNA as substrate assessed as stran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 44nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 7nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Human immunodeficiency virus 1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HIV1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 13nMAssay Description:Displacement of 20 nM [3H]GSK304649 from Human immunodeficiency virus 1 integrase by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase by strand transfer scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataKd:  3.30nMAssay Description:Displacement of 20 nM [3H]GSK304649 from Human immunodeficiency virus 1 integrase by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using labelled oligonucleotide substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity using labelled oligonucleotide substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HIV1 integrase using labelled oligonucleotide substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 recombinant integrase catalyzed strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed