BDBM50136767 2-[4-(5,7-Difluoro-2-phenyl-1H-indol-3-yl)-butyrylamino]-5-guanidino-pentanoic acid methyl ester::CHEMBL153158::L-803,087

SMILES COC(=O)C(CCCNC(N)=N)NC(=O)CCCc1c([nH]c2c(F)cc(F)cc12)-c1ccccc1

InChI Key InChIKey=OPNMQSFIGUSHDH-UHFFFAOYSA-N

Data  5 KI  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50136767   

TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity at human Somatostatin receptor type 5 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity at human Somatostatin receptor type 3 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 4.20nMAssay Description:Binding affinity at human Somatostatin receptor type 4 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity at human Somatostatin receptor type 1 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity at human Somatostatin receptor type 2 by [125I][Leu8,D-Trp22,Tyr25]SRIF-28 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards human Somatostatin receptor type 2 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 4.20nMAssay Description:Binding affinity towards human Somatostatin receptor type 4 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards human Somatostatin receptor type 3 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards human Somatostatin receptor type 5 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards human somatostatin receptor type 1 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards human somatostatin receptor type 3 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 4.20nMAssay Description:Binding affinity towards human somatostatin receptor type 4 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards human somatostatin receptor type 5 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards human somatostatin receptor type 2 using [125I][Leu8,D-Trp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataKi:  199nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataKi:  1.28E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataKi:  3.88E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136767(L-803,087 | CHEMBL153158 | 2-[4-(5,7-Difluoro-2-ph...)
Affinity DataKi:  4.72E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed