BDBM50085040 CHEMBL278994::L-796449::{3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid::{3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid(L-796449)

SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(coc12)-c1ccccc1

InChI Key InChIKey=KAPDPGZDHUCILF-UHFFFAOYSA-N

Data  7 IC50  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50085040   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataIC50: 94nMAssay Description:In vitro binding affinity for human PPAR gamma in SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataIC50: 94.0nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataIC50: 6nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataIC50: 54.0nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  7.90nMAssay Description:Binding affinity at human GST-tagged PPARdelta ligand binding domain after 1 hr by time-resolved FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataIC50: 94nMAssay Description:Displacement of radio-labeled full agonist from PPARgamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  18nMAssay Description:Transcriptional activation by human PPAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  9nMAssay Description:Transcriptional activation by human PPAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataIC50: 6nMAssay Description:In vitro binding affinity for human PPAR delta in SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  6nMAssay Description:Transcriptional activation by human PPAR deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataIC50: 54nMAssay Description:In vitro binding affinity for human PPAR alpha in SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  10nMAssay Description:Agonist activity for murine PPAR gamma receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  7.60E+3nMAssay Description:Agonist activity for murine PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity for Human PPAR gamma receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity for Human PPAR delta receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  23nMAssay Description:Agonist activity for murine PPAR delta receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50085040({3-Chloro-4-[3-(3-phenyl-7-propyl-benzofuran-6-ylo...)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity for Human PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed