BDBM50054538 (S)-3-[2-(1-Oxo-7-piperazin-1-yl-3,4-dihydro-1H-isoquinolin-2-yl)-acetylamino]-pent-4-ynoic acid::3-[2-(1-Oxo-7-piperazin-1-yl-3,4-dihydro-1H-isoquinolin-2-yl)-acetylamino]-pent-4-ynoic acid(L-767679)::CHEMBL57886::L-767679

SMILES OC(=O)C[C@H](NC(=O)CN1CCc2ccc(cc2C1=O)N1CCNCC1)C#C

InChI Key InChIKey=QTVKUFZTCJLGEJ-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054538   

TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054538(L-767679 | 3-[2-(1-Oxo-7-piperazin-1-yl-3,4-dihydr...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054538(L-767679 | 3-[2-(1-Oxo-7-piperazin-1-yl-3,4-dihydr...)
Affinity DataKd:  50nMAssay Description:Binding affinity to resting form of alpha IIb/beta3 integrin by flow cytometry using fluorescein ligand L-726,745 displacement from human platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054538(L-767679 | 3-[2-(1-Oxo-7-piperazin-1-yl-3,4-dihydr...)
Affinity DataKd:  0.560nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50054538(L-767679 | 3-[2-(1-Oxo-7-piperazin-1-yl-3,4-dihydr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed