BDBM50040671 1-[5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-m-tolyl-urea::CHEMBL349291::L-740,093

SMILES CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)N1CC2CCC(CC2)C1

InChI Key InChIKey=QYERABWMFRRINX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040671   

TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040671(L-740,093 | CHEMBL349291 | 1-[5-(3-Aza-bicyclo[3.2...)
Affinity DataIC50: 0.530nMAssay Description:Binding activity against Cholecystokinin type B receptor from guinea pig cortex using [125]BH CCK-8s as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50040671(L-740,093 | CHEMBL349291 | 1-[5-(3-Aza-bicyclo[3.2...)
Affinity DataIC50: 20nMAssay Description:Binding activity against Cholecystokinin type A receptor from rat pancreas using [125]BH CCK-8s as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetCholecystokinin(Pig)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50040671(L-740,093 | CHEMBL349291 | 1-[5-(3-Aza-bicyclo[3.2...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50040671(L-740,093 | CHEMBL349291 | 1-[5-(3-Aza-bicyclo[3.2...)
Affinity DataKi:  1.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details
PubMed