BDBM82514 1-[[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-[(hexahydro-1H-azepin)-1-yl]-1H-1,4-benzodiazepin]-3-yl]-3-(3-methylphenyl)urea::CHEMBL543712::L-737,415::L-738416

SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)N1CCCCCC1

InChI Key InChIKey=ZMUBIYUMHFIWON-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 82514   

TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM82514(L-738416 | 1-[[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-[...)
Affinity DataIC50: 1.40nMAssay Description:Binding activity against Cholecystokinin type B receptor from guinea pig cortex using [125]BH CCK-8s as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM82514(L-738416 | 1-[[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-[...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding activity against Cholecystokinin type A receptor from rat pancreas using [125]BH CCK-8s as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetCholecystokinin(Pig)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82514(L-738416 | 1-[[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-[...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM82514(L-738416 | 1-[[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-[...)
Affinity DataKi:  3.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details
PubMed